GLUTAMINE, GLUTAMIC ACID, AMMONIA ADMINISTRATION, AND TISSUE GLUTAMINE

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Glutamine, glutamic acid, ammonia administration, and tissue glutamine.

Despite the recent revival of interest in amide-nitrogen metabolism in animal tissues, only limited information is available on the effect of glutamine administration on the glutamine content of blood and tissues. Bessman et al. (1) found that glutamine was not converted to glutamic acid during intestinal absorption. More recently, this same group of workers (2) has studied the uptake of glutam...

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The absorption of glutamic acid and glutamine.

The occurrence of free glutamine in plant tissue extracts has been recognized for a considerable time, but its presence in the protein-free filtrates of mammalian tissues was established only recently (1). The functional significance of the free amide in tissues cannot be appreciated without a knowledge of its quantitative relationship to glutamic acid and of the biological mechanisms regulatin...

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Quantitative determination of glutamine and glutamic acid.

Abel, J. J. & Geiling, E. M. K. (1925). J. Pharmacol. 25,423. Bergmann, M., Fruton, J. S. & Pollok, H. (1939). J. biol. Chem. 127, 643. Blatherwick, N. R., Bischoff, F., Maxwell, L. C., Berger, J. & Sahyun, M. (1927). J. biol. Chem. 72, 57. Brand, E. & Kassell, B. (1941-2). J. gen. Physiol. 25, 167. du Vigneaud, V. (1927). J. biol. Chem. 75, 393. Fruton, J. S. (1946). J. biol. Chem. 166, 721. G...

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Ammonia and brain glutamine: inhibition of glutamine degradation by ammonia.

(the concentration used for radioautography), the uptake was mainly into the inner retina. However, as the exogenous taurine concentration was decreased to > 1 p~ the percentage of label accumulated by the photoreceptor layer increased with respect to the total uptake (Table 1). Further studies were carried out with the use of lOmin incubations and exposing the retinas to exogenous taurine conc...

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Glutamine, glutamic acid, and glycolysis in Bacillus subtilis.

The effect of glutamic acid and glutamine on glycolysis is one of the few examples of a direct and apparently specific action of amino acids on a particular phase of carbohydrate metabolism. Glutamine has been shown to stimulate glycolysis in Streptococcus hemolyticus (1) and in iron-deficient cells of Clostridium tetuni (2). Glutamine, glutamic acid, and related compounds have also been report...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1951

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)44896-x